Vol. 6 nº 4 - Oct/Nov/Dec de 2012
Original Article Páginas: 286 a 289

Basal ganglia lesions in subacute sclerosing panencephalitis

Authors Kelson James Almeida1; Sonia Maria Dozzi Brucki1; Maria Irma Seixas Duarte2; Carlos Augusto Gonçalves Pasqualucci3; Sérgio Rosemberg3; Ricardo Nitrini1


keywords: subacute sclerosing panencephalitis, measles, magnetic resonance imaging.

The parieto-occipital region of the brain is the most frequently and severely affected in subacute sclerosing panencephalitis (SSPE). The basal ganglia, cerebellum and corpus callosum are less commonly involved. We describe a patient with SSPE confirmed by neuropathology based on brain magnetic resonance imaging showing extensive basal ganglia involvement and no significant involvement of other cortical structures. Though rarely described in SSPE, clinicians should be aware of this involvement. SSPE should be kept in mind when changes in basal ganglia signal are seen on brain magnetic resonance imaging with or without involvement of other regions of the human brain to avoid erroneous etiological diagnosis of other pathologies causing rapidly progressive dementia.


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