Vol. 7 nº 1 - Jan/Feb/Mar de 2013
Original Article Páginas: 96 a 103

Functional profile of patients with behavioral variant frontotemporal dementia (bvFTD) compared to patients with Alzheimer's disease and normal controls

Authors Thais Bento Lima-Silva1; Valéria Santoro Bahia1; Viviane Amaral Carvalho2; Henrique Cerqueira Guimarães2; Paulo Caramelli2; Márcio Balthazar3; Benito Damasceno3; Cássio Machado de Campos Bottino4; Sônia Maria Dozzi Brucki1; Ricardo Nitrini1; Mônica Sanches Yassuda1

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keywords: behavioral variant frontotemporal dementia, functional status, dependence.

ABSTRACT:
There are few studies describing the functional changes in behavioral variant frontotemporal dementia (bvFTD) and it is not clear which aspects of functionality are affected by the disease.
OBJECTIVE: The aim of the present investigation was to characterize the functional profile of patients previously diagnosed with bvFTD.
METHODS: The sample consisted of 31 patients diagnosed with bvFTD, who were compared to patients with Alzheimer's disease (AD) (n=31) and to healthy control subjects (NC) (n=34), matched for schooling and age. bvFTD and AD patients were matched by severity of dementia. The protocol included the Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS), Direct Assessment of Functional Status (DAFS-BR), Functional Activities Questionnaire (PFAQ), Disability Assessment for Dementia (DAD) and the Clinical Dementia Rating scale (CDR).
RESULTS: The group with bvFTD showed worse performance on Initiation and Planning/Organization in the DAD and on ability to feed oneself in the DAFS-BR, as well as higher scores on the PFAQ, suggesting greater dependence in the bvFTD group.
CONCLUSION: The results suggest that individuals with bvFTD display greater functional impairment compared to AD patients with a similar degree of dementia severity and to healthy controls. Direct assessment of functionality proved unable to clearly differentiate between the dementia subtypes.

 

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