Vol. 12 nº 1 - Jan/Feb/Mar de 2018
Original Article Páginas: 40 a 44

Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects

Authors Marcelo Antônio Oliveira Santos1; Lucas Soares Bezerra1; Carolina da Cunha Correia2; Igor Silvestre Bruscky2,3


keywords: vascular dementia, elderly, behavioral symptoms, neuropsychiatric symptoms.

Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases.
OBJECTIVE: To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD) in a referral hospital for dementia.
METHODS: A descriptive, retrospective study was carried out from 2014 to 2017 involving elderly individuals (≥60 years) with VA or MxD. Patients presenting other forms of dementia or in use of medication that mimics cognitive disorders were excluded. The 12-item Neuropsychiatric Inventory was used to assess neuropsychiatric symptoms (NPS).
RESULTS: 81.1% of the patients presented NPS and only 15% had two or more symptoms. Apathy was the most frequent NPS (56.6%). There was an association between CDR score 1 or 2 and NPS (OR = 6.16, 95% CI: 1.36-27.9, p = 0.02).
CONCLUSION: Most patients had a single symptom, predominantly apathy. There was an association between mild-to-moderate dementia and NPS.


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